The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
Donate online now using the button below. RCPA Foundation thanks you for your generous support. All funds raised will be allocated to the RCPA Foundation Pathology Education Outreach Fellowship.
Eve Propper Events and Sponsorship Manager Ph: +61 2 8356 5806 Fax: +61 2 8356 5828 Email: evep@rcpa.edu.au
Rachel Johnson Events and Grants Coordinator Ph: +61 2 8356 5852 Fax: +61 2 8356 5828 Email: rachelj@rcpa.edu.au
Keywords: 5 indole acetic acid, 5-hydroxyindole acetate
24 h urine collection with HCl as preservative; patient must be on a diet free of fruit and nuts for three days prior to and during collection.
Exclusion of some drugs may be required - consult pathologist.
HPLC. Spectrophotometric and fluorescence assays are not reliable.
< 50 µmol/24h
Detection of carcinoid tumours.
Increased 24 h excretion of HIAA is found in carcinoid tumours particularly if metastasis to the liver or beyond has occurred.
Urinary excretion may be normal if the tumour is confined to the portal circulation.
More recently, measurement of serotonin in platelets has been advocated and may be the most sensitive indole marker for the detection of carcinoid tumours.
Some drugs and foods may interfere with some methods - consult pathologist.
Kema IP et al. J Chromatogr B Biomed Sci Appl 2000; 747: 33-48.
Page last updated:
The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
Read More
Copyright © 2020 RCPA. All rights reserved.