The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: ALT, Alanine transaminase, Glutamic pyruvic transaminase, SGPT
5 mL blood in lithium heparin or plain tube.
Spectrophotometry.
Adult: < 35 U/L
Neonate: < 50 U/L
Detection and monitoring of liver cell damage.
Increased ALT levels are associated with hepatocellular damage.
ALT is more specific for hepatocellular damage than is AST or LD and remains elevated for longer, due to its longer half-life.
The AST/ALT ratio is typically > 1 in alcoholic liver disease and < 1 in non-alcoholic liver disease.
ALT may be elevated in skeletal muscle disease but the degree of elevation is much less than for AST and CK.
Rochling FA. Clin Cornerstone 2001; 3: 1-12.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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