The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: ALP, Alk phos
5 mL blood in lithium heparin or plain tube.
See Table 6.
Higher levels are seen in the third trimester of pregnancy and in individuals over 50 years of age.
Investigation of hepatobiliary or bone disease.
Increased levels in liver disease (particularly in association with cholestasis), bone disease (with increased osteoblastic activity eg, Paget's disease), some bony metastases (especially prostate and breast), and at times in malignancy without liver or bone metastases (Regan isoenzyme).
May also be elevated in some gastrointestinal diseases or due to a macroenzyme.
Alkaline phosphatase isoenzymes are rarely necessary to identify the source of an elevated ALP.
Marked but transient elevation of ALP may be seen in children (Benign hyperphosphatasia).
Abnormal dentition and fragile bones with decreased ALP characterise the autosomal recessive disease hypophosphatasia.
Rochling FA. Clin Cornerstone 2001; 3(6): 1-12.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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