The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Blood group typing, BG, ABO subgroup
10 mL blood in plain tube; for some methods, blood in EDTA is preferred - consult pathologist.
Careful labelling of tube, with correct patient details (name, date of birth, identification number) and collection date is essential.
ABO and Rh(D) typing performed routinely.
Patient's red cells tested with anti-A and anti-B sera for ABO (forward) group; with anti-D antiserum for Rh(D) group.
Patient's serum tested with A1 and B cells to check ABO (reverse) group.
Tests are based on the detection of red cell agglutination.
See also Blood group and antibody screen.
Blood grouping is performed prior to possible transfusion, organ transplantation, in pregnancy and investigating certain neonatal conditions. Blood group may aid in interpretation of von Willenbrand studies.
Extended phenotyping (typing for other red cell antigens) may be necessary for patients requiring transfusion when alloantibodies have been detected, for assessment of risk of haemolytic disease of the newborn, and in newly presenting patients with haematological disease where ongoing transfusion support will be required.
Pattern of agglutination determines ABO and Rh(D) blood groups.
Guidelines for Pre-transfusion Testing. 4th ed. Sydney: Australasian Society of Blood Transfusion, 2002. Available at http://www.anzsbt.org.au/publications/documents/anzsbtguide_nov02b.pdf.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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