The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Trephine needle biopsy, open surgical biopsy or fine needle aspiration biopsy. The type of biopsy depends on the suspected diagnosis.
Fresh tissue is used for microbiological culture and cytogenetics (if indicated). In the majority of cases consultation between pathologist, radiologist and clinical staff is essential.
Frozen section is uncommon as calcified tissue is unsuitable
Fixed tissue: light microscopy, morphometry and molecular genetics. If metabolic bone disease is suspected, pre-biopsy administration of tetracycline (in vivo tetracyline labelling) may be indicated - consult laboratory staff.
May be indicated to establish the diagnosis of bone cysts, osteomalacia, rickets, osteoporosis, Paget's disease, renal osteodystrophy, hyperparathyroidism, suspected osteomyelitis, and suspected primary and secondary neoplasms.
The report by the pathologist will address the specific clinical problem such as diagnosis of demineralisation disorder, morphometric analysis for metabolic bone disease, identification and classification of benign tumours, and primary and secondary malignancy.
See also Bone marrow biopsy.
Rosai J. Rosai and Ackerman's Surgical Pathology. 10th Ed. Edinburgh: Elsevier, 2011; Chapters 23 and 24.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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