Assessment of underlying cause of abnormal Full blood count and/or Blood film, if appropriate.
Diagnosis, staging and progress of leukaemias, Myelodysplastic syndromes, Myeloproliferative neoplasms, myeloma, lymphomas.
Investigation of Leucoerythroblastic anaemia; possible bone marrow infiltration with metastatic carcinoma, amyloid, granulomatous disorders.
Required for diagnosis of Sideroblastic anaemia.
Assessment of whether reduced cell numbers are due to failure of production or peripheral destruction; diagnosis of marrow hypoplasia or aplasia.
Occasionally useful for the diagnosis of infection, eg, Mycobacterial infection, Typhoid, Brucellosis.
Rarely indicated for the investigation of Lysosomal storage disease.
See also Cell immunophenotyping, Flow cytometry, Cytogenetics - oncology, Molecular genetics and Cytochemistry.