The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Urinary calculi
Calculus obtained from spontaneous passage or surgical intervention
Commonly a series of spot tests are performed on pulverised, dissolved calculus. The mineral composition is then deduced from the relative amounts of each compound.
Calcium:spectrophotometry, atomic absorption spectrophotometry
Oxalate: spectrophotometry, titration
Cystine: visual, qualitative test
Carbonate: visual, qualitative test
Infrared spectroscopy and X-ray diffraction provide more definitive identification.
Identification of risk factors for stone recurrence. May guide extracorporeal lithotripsy.
Stones containing calcium may indicate hypercalciuria.
Uric acid stones, or stones with a uric acid nidus, may indicate strongly acidic overnight urine or hyperuricosuria.
Oxalate stones may indicate hyperoxaluria. Magnesium ammonium phosphate ('triple phosphate') stones indicate bacterial infection.
Cystine stones indicate cystinuria.
Xanthine stones indicate xanthinuria or treatment with allopurinol.
Stones that do not dissolve in acid are usually factitious.
Coe FL et al.N Engl J Med 1992; 327: 1141-1152.
Tiselius HG et al. Eur Urol 2001; 40(4): 362-3671.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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