The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Tegretol
5 mL blood in lithium heparin or plain tube, collected immediately prior to the next dose.
Immunoassay, HPLC.
20-40 µmol/L (6-12 mg/L).
Therapeutic drug monitoring.
Levels are related to the dose and the time since the previous dose.
Mean half-life is 35 h (range 18-65 h) early in treatment, often becoming shorter (12-24 h) with prolonged treatment due to enzyme induction by the drug (autoinduction).
Carbamazepine epoxide, a major metabolite, is also active pharmacologically. Its level may be available if analysis is done by HPLC.
Monaco F et al. J Int Med Res 1979; 7: 152-157.
Glauser TA and Pippenger CE. Epilepsia. 2000; 41:6-15.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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