The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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The patient should rest for 30 minutes after insertion of an indwelling cannula, to allow return to a basal state.
10 mL blood in an EDTA tube.
Some laboratories require a special EDTA/metabisulphite tube.
Specimen must be transported rapidly to the laboratory on melting ice, centrifuged without delay, and the plasma stored frozen.
HPLC, radiometric assay.
Varies with laboratory, typically:
Adrenaline: < 0.3 nmol/L
Noradrenaline: < 2.5 nmol/L
Dopamine: < 0.5 nmol/L
Have been used as an alternative to urine catecholamine studies in the diagnosis of Phaeochromocytoma (adrenaline, noradrenaline) or Neuroblastoma (dopamine). However, urine catecholamines or metanephrines are used more often. See Catecholamines urine and Metanephrines urine.
Plasma metanephrine assays are the preferred first line tests for Pheochromocytoma.
Elevated levels suggest the presence of tumour.
If clinical uncertainty exists and the tumour cannot be located by diagnostic imaging, a clonidine suppression test may be indicated. See Clonidine suppression test.
Lenders JW et al. Ann N Y Acad Sci 2002; 970: 29-40.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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