The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Total cholesterol, TC, Chol
5 mL blood in EDTA, lithium heparin, or plain tube; consult pathologist. Fasting (14 h) specimen is preferred. Prolonged tourniquet use can artefactually increase levels by up to 20%. See Table1.
Spectrophotometry.
For minimal risk of coronary artery disease, the Australian National Heart Foundation recommends a treatment target of < 4.0 mmol/L.
Assessment of lipid status, particularly as a risk factor for coronary artery disease.
To assess atherosclerotic risk, cholesterol should be performed with triglyceride and HDL assays, as part of a global risk assessment.
The optimal level is <4.0 mmol/L and higher levels are associated with an increased risk of coronary artery disease in all age groups. The cause may be primary (familial hypercholesterolaemia and other genetic disorders) or secondary (associated with eg, biliary obstruction, hypothyroidism, nephrotic syndrome).
Levels are reduced for up to 8 weeks with acute illness (eg, myocardial infarction, acute infection) and assessment should not be attempted during this time.
National Vascular Disease Prevention Alliance. Guidelines for the management of absolute cardiovascular disease risk. Melbourne: National Stroke Foundation; 2012. https://www.heartfoundation.org.au/images/uploads/publications/Absolute-CVD-Risk-Full-Guidelines.pdf
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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