The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Folate RBC, Red cell folate, RCF
5 mL blood in EDTA tube and 5 mL blood in plain tube.
Check with laboratory.
Red cell: 360-1400 nmol/L
Serum: 7-45 nmol/L.
Investigation of patients with a high MCV and/or changes in red cell morphology on blood film suggestive of Megaloblastic anaemia. Patients at risk of folate deficiency include those with chronic haemolytic anaemia, Malabsorption, pregnancy and those on certain medications (eg, anticonvulsants).
Serum folate alone is of little diagnostic value as levels may be reduced with a short term decrease in dietary intake and in systemic illness.
Red cell and serum folate levels are low in Megaloblastic anaemia due to folate deficiency.
In vitamin B12 deficiency, serum folate may be normal or raised, with a normal or low red cell folate.
Low serum folate with a normal red cell folate may be seen in systemic illness and with a short term decrease in folate intake.
Hoffman R et al. Haematology Basic Principles and Practice. 2nd ed 1995. Churchill Livingstone.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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