The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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5 mL blood in anticoagulated or plain tube.
Refer to laboratory. Approximate range given below.
Investigation of possible intra- or extra-vascular haemolysis.
Value limited by low sensitivity and specificity.
May be used as a measure of ongoing haemolysis in TTP during plasma exchange therapy.
Haptoglobin binding of free haemoglobin results in removal of the complex from the circulation.
Reduced levels occur in haemolysis (particularly intravascular), megaloblastic anaemia (red cell turnover in marrow) following blood transfusion, massive tissue haemorrhage, and hepatocellular disease.
Congenital absence of haptoglobin has also been recognised.
High levels may be seen in pregnancy, with steroid or oestrogen therapy, in conditions associated with an acute phase response, and in biliary obstruction.
Pre-existent high levels may mask haemolysis.
Owen JA et al. J Clin Pathol. 1969. 13: 163-164.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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