The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Haemoglobin A1c, Glycated Hb, GHB, Glycosylated haemoglobin, Glycohaemoglobin
5 mL blood in lithium heparin tube.
Chromatography, electrophoresis, immunoassay.
Methods may be specific for HbA1c or may measure total glycohaemoglobin (HbA1).
HbA1c: 3.5 - 6.0% (15-42 mmol/mol)
HbA1c: 6.1 - 6.4% (43-47 mmol/mol) indeterminate
HbA1c: ≥ 6.5% (≥48 mmol/mol) diagnostic of diabetes.
Diabetes mellitus: monitoring of glycaemia over previous three months. Diagnosis of diabetes.
The result reflects the average glucose concentration over the life of the red cells although some methods give a falsely high reading if the patient is hyperglycaemic when the blood is collected.
HbA1c levels < 8% indicate good control.
Levels will be lower than appropriate for the degree of diabetic control in the presence of a reticulocytosis.
See also Fructosamine.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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