The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: HPV, HPV PCR
Cells or tissue obtained by Pap smear (cervix), cytology collection or biopsy of lesion.
Microscopy, immunoperoxidase staining, HPV-DNA probe with or without prior PCR amplification.
To detect presence of papillomavirus infection when this is suspected but is not evident clinically.
Typing of virus infection to determine relative risk of developing cancer.
The occurrence of genital cancer (especially cervical) is greatly increased in the presence of 'high risk' HPV types (types 16,18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68).
Sensitivity with PCR methodology is greater than methods utilising DNA probes alone.
Cuzik J et al. Lancet. 2003; 362: 1871-1876.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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