The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: IGF1, Insulin growth factor 1, Somatomedin C, Insulin-like growth factor
5 mL blood in a plain tube.
Immunoassay.
Varies with age, gender and pubertal status.
Adult: 13-50 nmol/L.
Diagnosis of acromegaly or gigantism.
Diagnosis of Laron dwarfism.
Investigation of Hypopituitarism.
Limited value in the assessment of growth hormone deficiency or nutritional status.
Levels are increased in acromegaly, and the test is used in the initial assessment of patients, prior to a Growth hormone suppression test.
Its diagnostic value is limited at the time of puberty, during Malnutrition and with severe illness.
In Laron dwarfism growth hormone is not reduced but IGF-I is reduced.
Low IGF-I has been used as a test for protein malnutrition but interpretation is difficult in view of changes in plasma IGF-binding proteins.
Brabant G. Eur J Endocrinol. 2003; 148:2: 15-20.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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