The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Lesion or organ biopsy eg, skin, kidney, lung; must be fresh, unfixed and delivered immediately to the laboratory.
Immunofluorescence transport medium can be used if the laboratory is distant or delivery is delayed.
Consult laboratory staff prior to obtaining and sending the specimen to ensure optimal sampling and processing conditions.
In special circumstances, antigen retrieval can be used for immunofluorescence of fixed tissue.
The results of this are, however, often unsatisfactory as there are problems with reliability, sensitivity and altered staining patterns.
Detection of immunoglobulin and complement deposition, especially in renal and skin biopsies. Detection of viral or bacterial antigens eg, cytomegalovirus, mycobacteria, legionella.
Positive staining indicates the presence of the antigen.
The pattern and localisation of staining is an aid in the diagnosis of some bullous and inflammatory skin diseases and immune complex and antibody-mediated renal diseases.
Detection of viral and bacterial antigens confirms the presence of a specific infection.
Taylor CR and Cote RJ. Immunomicroscopy: A diagnostic tool for the Surgical Pathologist. Volume 19 in the major problems in pathology series. 3rd ed. 2005. Elsevier Saunders.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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