The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Influenza antigen, Influenza virus antigen
Nasal swab, nasal wash or aspirate, throat swab for IF.
Dry swabs, that is not in transport medium, are required for rapid immunoassays and should be tested within 1 hour of collection.
Dry swabs should also be collected for PCR testing.
Nucleic acid detection by immunoassay, IF, nucleic acid detection after amplification (PCR).
Nucleic acid detection by immunoassay allows point of care testing for rapid diagnosis of acute influenza due to influenza virus types A and B, and thus can be used to guide the use of antiviral treatment.
IF and PCR testing are more sensitive.
A positive result confirms infection with influenza types A and B.
Rapid immunoassays generally do not distinguish between types A and B, whereas IF testing may.
Rapid immunoassays have a sensitivity of ~80%, so a negative result does not rule out the diagnosis.
False positives are uncommon.
Cox NJ and Subbarao K. Lancet. 1999; 354: 1277-1282.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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