The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: LD, LDH
5 mL blood in lithium heparin or plain tube.
Method and age dependent. See Table 6.
Of no value in the diagnosis of Myocardial infarction.
It is occasionally useful in the assessment of patients with liver disease or malignancy (especially lymphoma, seminoma, hepatic metastases); anaemia when haemolysis or ineffective erythropoiesis is suspected.
Although it may be elevated in patients with skeletal muscle damage it is not useful in this situation.
The ubiquitous tissue distribution of LD makes it a non-specific indicator of disease.
Increased levels are found in Myocardial infarction, Liver disease, haemolysis, ineffective erythropoiesis, some malignancies (especially Lymphoma (non-Hodgkin), muscle disease, and numerous other disease processes involving tissue damage.
Haemolysis during collection, delays in processing, or refrigeration of unseparated blood may cause an artefactual increase in enzyme activity. See Table 1.
McComb RB. In: Homberger HA ed. Clinical and Analytical Concepts in Enzymology. 1983. College of American Pathologists.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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