Mean cell haemoglobin concentration
5 mL blood in EDTA tube.
Part of Full blood count; calculated by automated and semi-automated instruments or from manual results.
Arithmetically, MCHC is Hb divided by PCV.
|Reference Interval:|| |
Refer to laboratory. Some variation with method; adults and children 300-350 g/L.
Guide to investigation of anaemia.
Blood film should also be requested.
There is a rough correlation between low MCHC and hypochromia and between high MCHC and the presence of spherocytes.
Bain BJ. Blood cells: a practical guide. 4th Ed. 2007. Oxford: Blackwell Publishing.
Bain et al. Dacie and Lewis Practical Haematology. 11th Ed. 2012.