The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: PTH, Parathyroid hormone intact, Intact parathyroid hormone
10 mL blood in plain tube. Specimen transported rapidly to laboratory on melting ice.
1.0-7.0 pmol/L (method dependent).
Investigation of unexplained hypercalcaemia and hypocalcaemia.
Monitoring management of osteodystrophy in chronic renal failure.
The interpretation of PTH levels is dependent on the patient’s corrected calcium, or ionised calcium, at the time the blood specimen was taken.
In hyperparathyroidism the PTH level is increased or high normal in the presence of hypercalcaemia.
In most cases of hypercalcaemia associated with malignancy PTH level will be suppressed, often with an elevated PTHrP.
Hypoparathyroidism is associated with a low PTH.
Pseudohypoparathyroidism and other causes of hypocalcaemia are associated with a high PTH.
Effective management of osteodystrophy in chronic renal failure is associated with relatively little or no elevation of PTH.
See also Parathyroid hormone related protein.
St John A. Clin Biochem Rev 1995; 16: 27-36.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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