The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: PO4, PHOS
5 mL blood in lithium heparin or plain tube.
Rapid separation is essential.
A fasting specimen should be collected if hypophosphataemia is suspected to be due to post-prandial depression of phosphate.
See Table 6.
Assessment of patients with renal failure, metabolic bone disease, hyper- and hypo-parathyroidism.
Increased phosphate levels are found in response to low parathyroid hormone levels (eg, Hypoparathyroidism, Hypercalcaemia due to malignancy and other non-parathyroid causes) and in renal failure.
Decreased levels of phosphate are usually found in patients with primary Hyperparathyroidism, in some cases of Hypercalcaemia associated with malignancy, in renal tubular disorders and in patients using magnesium and aluminium containing antacids.
Levels may be decreased during prolonged intravenous therapy if phosphate supplementation is inadequate. Phosphate levels may also be decreased following a carbohydrate-rich meal, due to cellular uptake of phosphate.
Numerous other conditions can affect serum phosphate levels.
Yu G.C. et al. West J Med. 1987; 147: 569-576.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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