Plasminogen activator inhibitor
This assay is rarely performed and only in specialised laboratories.
4.5 mL blood added to 0.5 mL citrate.
Functional assay: PAI activity measured by urokinase inhibition.
|Reference Interval:|| |
Functional assay: 0-3.5 U/mL
Immunoassay: 4-43 ng/mL.
Rarely performed. Investigation of recurrent thrombotic episodes.
PAI is an inhibitor of the fibrinolytic system.
Elevated levels may be found in acute myocardial infarction, malignancy, pre-eclampsia, infectious disease, and following surgery (trauma).
Bain et al. Dacie and Lewis Practical Haematology. 11th Ed. 2012.