The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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A minimum of 2 g faeces; delivered to the laboratory within 5 h or frozen until delivered.
Spectrophotometry, fluorometry, HPLC.
Coproporphyrin: < 30 µmol/kg dry weight
Protoporphyrin: < 135 µmol/kg dry weight
Investigation of a patient with suspected porphyria. Faecal porphyrins are more likely to be abnormal in an asymptomatic patient than are urine porphyrins.
Faecal porphyrin excretion is normal in acute intermittent porphyria but is increased in porphyria variegata and coproporphyria. Faecal porphyrins (isocoproporphyrin) are also increased in porphyria cutanea tarda. Separation of porphyrins is carried out by specialised laboratories and allows identification of characteristic patterns and markers for the differential diagnosis of porphyrias and for the investigation of porphyria in remission.
Lecha M et al. Diagnosis and treatment of the hepatic porphyrias. Dermatol Ther. 2003;16(1):65-72. Review.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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