The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Urine sodium, Urine Na
Random or 24 h urine collection.
ISE, flame emission spectrophotometry.
In Hyponatraemia or hypovolaemic shock without acute tubular necrosis, urine sodium should be < 20 mmol/L and fractional excretion of sodium should be < 1.5%.
If extracellular fluid volume and plasma sodium are normal, urine sodium should equal intake minus non-renal losses, typically 75-300 mmol/24 h.
Investigation of Hyponatraemia.
Assessment of renal function in hypovolaemic shock.
Investigation of compliance with a low sodium diet.
Investigation of predisposing factors for hypercalciuria in patients with renal calculi.
Urinary sodium excretion exceeds 20 mmol/L in Hyponatraemia due to SIADH, diuretic therapy, or Addison’s disease.
In a patient with shock and oliguria a urinary sodium > 20 mmol/L or a fractional excretion of sodium > 1.5% suggests acute tubular necrosis.
High urine sodium increases urine calcium and predisposes to calculi containing calcium.
Halperin ML and Bohn D. Crit Care Clin. 2002; 18(2): 249-272.
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Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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