Streptococcus pneumoniae Ag
Keywords: Streptococcus pneumoniae antigen
Midstream or 'clean catch' urine. catheter or bladder aspirate specimen in a sterile container
In conjunction with microscopy and culture of respiratory tract specimens, testing of urine may assist in the diagnosis of pneumococcal pneumonia in adults.
Detection of Streptococcus pneumoniae antigen in the urine of an adult with pneumonia is suggestive that this is the aetiologic agent. Occasional false positives occur. The test is most sensitive in cases of severe and/or invasive disease. A negative test does not exclude infection. In children, use of this test does not distinguish between naso-pharyngeal carriage of the organism and lower respiratory tract infection.
Smith DM et al. J Clin Microbiol 2003 41(7); 2810-2813