The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Testosterone total, Dihydrotestosterone, Sex hormone binding globulin, SHBG
5 mL blood in plain tube.
The laboratory may estimate one or more of the following:
sex hormone binding globulin (SHBG);
free androgen index (from total testosterone and SHBG); or
Levels are method, age, gender and Tanner stage dependent.
Assessment of hirsutism or virilisation in females.
Investigation of testicular failure or precocious puberty in males.
Increased levels may be found in women with hirsutism or virilisation and in (phenotypic) women with total androgen insensitivity.
Levels are increased in males with precocious puberty.
Decreased levels are found in males with testicular failure, either primary or secondary to hypopituitarism.
In plasma, testosterone is bound to SHBG, so abnormal levels of SHBG may cause a discrepancy between free and total testosterone.
Allan CA and McLachlan RI. Aust Fam Physician 2003; 32: 422-427.
Hunter MH and Carek PJ. Am Fam Physician 2003; 67: 2565-2572.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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