The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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5 mL blood in plain tube.
Laboratory dependent usually between <30 and <40 µg/L. Thyroglobulin (Tg) should be undetectable in a patient who has had a total thyroidectomy.
Detection of tumour recurrence in thyroid cancer.
Investigation of suspected thyroiditis or thyrotoxicosis factitia. Thyroglobulin antibody (Tg Ab) should be measured every time Tg is measured as the former may cause false negative results with Tg assays.
Detectable levels in patients with thyroid cancer who have had a total thyroidectomy (and who should cease thyroid replacement therapy for 2 weeks prior to testing) indicates the presence of residual tumour.
Stimulation with recombinant TSH prior to testing has been recommended with conventional Tg assays. Highly sensitive assays may obviate the need for TSH stimulation. Levels in thyroiditis and thyrotoxicosis are high, but if thyrotoxicosis is due to self-medication with thyroid hormone, the level is suppressed.
Mazzaferri EL et al. J Clin Endocrinol Metab. 2003; 88(4): 1433-1441.
Spencer C et al. Curr Opin Endocrinol Diabetes Obes. 2014; 21(5): 394-404.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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