The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Typhoid antibody
5-10 mL blood in plain tube.
Agglutination (Widal) test to detect antibodies to O and H antigens.
The test is occasionally useful to support the diagnosis of enteric fever (Salmonella typhi, Salmonella paratyphi) if cultures are negative.
Investigation of pyrexia of unknown origin.
Antibodies to Vi antigen have been used for epidemiological purposes.
Culture is the definitive method for diagnosis of S. typhi or S. paratyphi infection.
Serology is of only limited value because false positives and negatives are common.
Increased titres are consistent with infection, the carrier state or immunisation.
For a patient who has not been immunised, a positive Widal test is one in which there is a four-fold rise in anti-O antibody or a titre of > 100 in a single blood sample taken in the first 3 weeks of the illness.
Parry CM et al. N Engl J Med. 2002; 347: 1770-1782.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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