The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Uric acid, UA
5 mL blood in lithium heparin or plain tube.
Female: 0.15-0.40 mmol/L
Male: 0.20-0.45 mmol/L.
Diagnosis and monitoring of gout and pregnancy-induced hypertension.
Monitoring of therapy in malignancies where there is a high rate of cell destruction and uric acid production.
Assists in the diagnosis of SIADH.
The likelihood of gout is low if the serum urate concentration is repeatedly below 0.42 mmol/L. The risk of developing gout is three times greater if the serum urate concentration is consistently above 0.42 mmol/L. However, a raised serum urate level alone is insufficient to diagnose gout.
Impaired renal function, pregnancy-induced hypertension, diuretics, fasting, hyperlactataemia, hyperketonaemia and low dose salicylates can all produce increased urate levels.
Hypouricaemia is seen in patients with a low purine intake, in SIADH, with hypouricaemic drugs (eg, allopurinol) and in the rare condition of xanthinuria.
Liote F. Curr Rheumatol Rep 2003; 5(3): 227-234.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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