The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Keywords: Vitamin D 25 hydroxy, Vitamin D 25 OH, 25 hydroxycholecalciferol, 25 OH Vitamin D, Cholecalciferol, Vitamin D3
5 mL blood in plain tube.
Immunoassay.
50-200 nmol/L.
Investigation of suspected rickets and osteomalacia (eg, Malabsorption, dietary deficiency).
Investigation of Osteoporosis.
Investigation of suspected vitamin D toxicity.
Vitamin D adequacy: ≥ 50 nmol/L at the end of winter (level may need to be 10–20 nmol/L higher at the end of summer, to allow for seasonal decrease).
Mild vitamin D deficiency: 30–49 nmol/L
Moderate vitamin deficiency: 12.5–29 nmol/L
Severe vitamin D deficiency: < 12.5 nmol/L
Toxicity: (Hypercalcaemia, hypercalciuria and nephrocalcinosis). Hypercalcaemia is not seen until serum 25-OHD levels reach 220 nmol/L and is generally not reported until levels reach 500 nmol/L
Nowson C et al. Med J Aust. 2012 Jun 18;196(11):686-7.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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